Research Advance in GP73 in the Clinical Diagnosis and Treatment of Patients with Chronic Hepatitis B

Golgi protein 73 (GP73) is a type II integrative membrane protein located in the cellular Golgi apparatus. Research shows, that in addition to protein processing, GP73 is involved in cell differentiation, intercellular signaling and apoptosis. With the development of proteomics technology, the relationship between GP73 and chronic hepatitis B has been gradually revealed. In this review, the clinical diagnostic value and the therapeutic prediction of GP73 in chronic hepatitis B in recent years are reviewed, to provide ideas for the diagnosis and treatment of patients with chronic hepatitis B.